Advances in Extracellular Vesicle Research Over The Past Decade Joshua A. Welsh, Deborah C. I. Goberdhan, Lorraine O’Driscoll, Edit I. Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A. P. Driedonks, Uta Erdbrügger, Dirk Strunk, Martin Wolf, et al. Advanced Healthcare Materials 2024 READ THE FULL ARTICLE
Chondrocyte Isolation from Loose Bodies-An Option for Reducing Donor Site Morbidity for Autologous Chondrocyte Implantation Martin Textor, Arndt Hoburg, Rex Lehnigk, Carsten Perka, Georg Duda, Simon Reinke, Antje Blankenstein, Sarah Hochmann, Andreas Stockinger, Herbert Resch, Martin Wolf, Dirk Strunk, Sven Geissler. International Journal of Molecular Sciences 2023 DOI: https://doi.org/10.3390/ijms24021484 READ THE FULL ARTICLE
Which risk factors determine cartilage thickness and composition change in radiographically normal knees? – Data from the Osteoarthritis Initiative. F. Eckstein, S. Maschek, A. Culvenor, L. Sharma, F.W. Roemer, G.N. Duda, W. Wirth. Open Osteoarthritis and Cartilage Open 2023 DOI: 10.1016/j.ocarto.2023.100365 READ THE FULL ARTICLE
Nesting behavior is associated with body weight and grip strength loss in mice suffering from experimental arthritis. Tamara Dietrich, Annette Aigner, Alexander Hildebrandt, Jérôme Weber, Mara Meyer Günderoth, Katharina Hohlbaum, Johannes Keller, Serafeim Tsitsilonis & Tazio Maleitzke. Scientific Reports 2023. DOI: https://doi.org/10.1038/s41598-023-49720-y READ THE FULL ARTICLE
The dual pro‑inflammatory and bone‑protective role of calcitonin gene‑related peptide alpha in age‑related osteoarthritis. Alexander Hildebrandt, Tamara Dietrich, Jérôme Weber, Mara Meyer Günderoth, Sijia Zhou, Florian N. Fleckenstein, Shan Jiang, Tobias Winkler, Georg N. Duda, Serafeim Tsitsilonis, Johannes Keller and Tazio Maleitzke. Arthritis Research & Therapy 2023. DOI: https://doi.org/10.1186/s13075-023-03215-3 READ THE FULL ARTICLE
Biomarkers for osteoarthritis: Current status and future prospects. Ali Mobasheri, Christian S. Thudium, Anne-Christine Bay-Jensen, Tazio Maleitzke, Sven Geissler, Georg N. Duda, Tobias Winkler. Best Practice & Research Clinical Rheumatology 2023. DOI: 10.1016/j.berh.2023.101852 READ THE FULL ARTICLE
A sample rapid MRI acquisition protocol supporting assessment of multiple articular tissues and pathologies in early and advanced knee osteoarthritis. Wisser A, Walter-Rittel TC, Chaudhari A, Brisson NM, Maleitzke T, Duda GN, Wirth W, Winkler T, Eckstein F,Osteoarthritis Imaging 2024, DOI:10.1016/j.ostima.2024.100221 READ THE FULL ARTICLE
Minimal information for studies of extracellular vesicles (MISEV2023).
Joshua A. Welsh, Deborah C. I. Goberdhan, Lorraine O’Driscoll, Edit I. Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A. P. Driedonks, Uta Erdbrügger, Dirk Strunk, Martin Wolf, et al. Journal of Extracellular Vesicles 2024. DOI: 10.1002/jev2.12404 READ THE FULL ARTICLE
The Design of a Sample Rapid Magnetic Resonance Imaging (MRI) Acquisition Protocol Supporting Assessment of Multiple Articular Tissues and Pathologies in Knee Osteoarthritis.
Felix Eckstein, Thula Cannon Walter-Rittel, Akshay Chaudhari, Nicholas Brisson, Tazio Maleitzke, Georg N. Duda, Anna Wisser, Wolfgang Wirth, Tobias Winkler. Osteoarthritis & Cartilage Open 2024- accepted for publication DOI: 10.1016/j.ocarto.2024.100505 READ THE FULL ARTICLE
Sexual dimorphism in peri-articular tissue anatomy – More keys to understanding sex-differences in osteoarthritis?
Felix Eckstein, Reinhard Putz, Wolfgang Wirth. Osteoarthritis & Cartilage Open 2024. DOI:10.1016/j.ocarto.2024.100485 READ THE FULL ARTICLE
In Vitro Transcribed mRNA Immunogenicity Induces Chemokine-Mediated Lymphocyte Recruitment and Can Be Gradually Tailored by Uridine Modification. Drzeniek NM, Kahwaji N, Picht S, Dimitriou IM, Schlickeiser S, Moradian H, Geissler S, Schmueck-Henneresse M, Gossen M, Volk HD. Advanced Science 2023. DOI:10.1002/advs.202308447 READ THE FULL ARTICLE
The clusterin connectome: Emerging players in chondrocyte biology and putative exploratory biomarkers of osteoarthritis.
Kovács, Patrik; Pushparaj, Peter Natesan; Takács, Roland; Mobasheri, Ali; Matta, Csaba. Frontiers in immunology 2023. DOI:10.3389/fimmu.2023.1103097 READ THE FULL ARTICLE
Tissue engineering and future directions in regenerative medicine for knee cartilage repair: a comprehensive review.
Primorac, Dragan; Molnar, Vilim; Tsoukas, Dimitrios; Uzieliene, Ilona; Tremolada, Carlo; Brlek, Petar; Klarić, Emil; Vidović, Dinko; Zekušić, Marija; Pachaleva, Jolita; Bernotiene, Eiva; Wilson, Adrian; Mobasheri, Ali.Croatian medical journal 2024. DOI:10.3325/cmj.2024.65.268 READ THE FULL ARTICLE
Prognostic implications of a CD8⁺ TEMRA to CD4⁺ Treg imbalance in mandibular fracture healing: a prospective analysis of immune profiles.
Voss JO, Pivetta F, Elkilany A, Schmidt-Bleek K, Duda GN, Odaka K, Dimitriou IM, Ort MJ, Streitz M, Heiland M, Koerdt S, Reinke S, Geissler S. Frontiers in Immunology 2024. DOI: https://doi.org/10.3389/fimmu.2024.1476009 READ THE FULL ARTICLE
Long-term in vitro maintenance of plasma cells in a hydrogel-enclosed human bone marrow microphysiological 3D model system.
Martini S, Drzeniek NM, Stark R, Kollert MR, Du W, Reinke S, Ort M, Hardt S, Kotko I, Kath J, Schlickeiser S, Geißler S, Wagner DL, Krebs AC, Volk HD. Biofabrication DOI: https://doi.org/10.1088/1758-5090/ad5dfe READ THE FULL ARTICLE
Obesity-induced fibrosis in osteoarthritis: Pathogenesis, consequences and novel therapeutic opportunities.
Henriques J, Berenbaum F, Mobasheri A. Osteoarthritis and Cartilage Open DOI: 10.1016/j.ocarto.2024.100511 READ THE FULL ARTICLE
TissueGene-C induces anti-inflammatory activity and M2 macrophage polarization via activation of prostaglandin E2 signaling.
Tran H, Tauro W, Mobasheri A, Noh MJ. Cytotherapy DOI: 10.1016/j.jcyt.2024.11.005 institutional repository https://oulurepo.oulu.fi/handle/10024/53490 READ THE FULL ARTICLE
Development of a Microphysiological Cartilage-on-Chip Platform for Dynamic Biomechanical Stimulation of Three-Dimensional Encapsulated Chondrocytes in Agarose Hydrogels.
Peitso V, Sarmadian Z, Henriques J, Lauwers E, Paggi CA, Mobasheri A. Current Protocols 2024. DOI: 10.1002/cpz1.70079 READ THE FULL ARTICLE
Comment on: “Surgical restabilization reduces the progression of post-traumatic osteoarthritis initiated by ACL rupture in mice” (Lin et al., 2024).
Maleitzke T, Bolander J, Mobasheri A, Fleckenstein FN, Eckstein F, Brisson NM, Winkler T. Osteoarthritis and Cartilage DOI: 10.1016/j.joca.2025.02.002 institutional repository https://oulurepo.oulu.fi/handle/10024/56539 READ THE FULL ARTICLE
Aminooxy Biotin-Based Characterization of the Surfaceome of Chondrogenic Cells.
Kovács P, Boocock DJ, Coveney C, Mobasheri A, Matta C. The Surfaceome: Methods and Protocols DOI: 10.1007/978-1-0716-4434-8_5 via institutional repository https://oulurepo.oulu.fi/handle/10024/55779
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Introduction: Methods for Studying the Plasma Membrane and the Surfaceome.
Takács R, Mobasheri A, Matta C.The Surfaceome: Methods and Protocols DOI: 10.1007/978-1-0716-4434-8_1 institutional repository https://oulurepo.oulu.fi/handle/10024/56469 READ THE FULL ARTICLE
Gene therapy pipelines for osteoarthritis: current innovations, operational challenges, and future directions.
Peitso V, Ng K, Ellis R, Reginster J-Y, Evans CH, Mobasheri A. Connective Tissue Research DOI: 10.1080/03008207.2025.2520319 READ THE FULL ARTICLE
Insights into chondrocyte populations in cartilaginous tissues at the single-cell level.
Matta C, Takács R, Dvir-Ginzberg M, Richardson SM, Pelttari K, Pattappa G, Risbud MV, Mobasheri A. Nature Reviews Rheumatology DOI: 10.1038/s41584-025-01275-0 institutional repository https://oulurepo.oulu.fi/handle/10024/59713
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White paper – A proposal towards objective biomechanical metrics as novel endpoints to document improvements in musculoskeletal function and mobility.
Alves SA, Brisson NM, Agres AN, Heyland M, Mobasheri A, Hunter DJ, Winkler T, Duda GN. Osteoarthritis and Cartilage Open DOI: 10.1016/j.ocarto.2025.100648 READ THE FULL ARTICLE
Looking Inwards: The Role of Self-Care, Self-Management and Self-Healing in Musculoskeletal Pain.
McSwan J, Panwar CE, Mobasheri A. Musculoskeletal Care DOI: 10.1002/msc.70169 READ THE FULL ARTICLE
Omics-driven insights into the molecular pathways driving osteoarthritis pathogenesis.
Welsing PMJ, El Bouhaddani S, Zhu L, Nijhof NC, Mastbergen SC, Wen C, Bacardit J, Ruiz-Romero C, Blanco FJ, Mobasheri A. Connective Tissue Research DOI: 10.1080/03008207.2025.2541291 READ THE FULL ARTICLE
Rapidly progressive osteoarthritis (RPOA) in companion animals treated with bedinvetmab (Librela™): an expected pathophysiological phenomenon or a cause for concern?
Mobasheri A, Hanson P, Larkin J. Frontiers in Veterinary Science 2025. DOI: 10.3389/fvets.2025.1640217 READ THE FULL ARTICLE
Magnetic Resonance Imaging (MRI) Transverse Relaxation Time (T2) For Non-Invasive Assessment of Cartilage Composition… A Selfie Review of 15 Years of Funding & Publication.
Eckstein F, Bangerter N, Wirth W. Paracelsus Proceedings of Experimental MedicineDOI: 10.33594/000000842 READ THE FULL ARTICLE
Human Cardiac Microtissues Display Improved Engraftment and Survival in a Porcine Model of Myocardial Infarction.
Demkes E, Cervera‑Barea A, Ebner‑Peking P, Wolf M, Hochmann S, Scheren AS, Bijsterveld M, van Oostveen CM, Jansen M, Visser J, Triebert W, Halloin C, Dobbe JGG, de Vos J, Schürz M, Danmayr J, Aalders MCG, Boink GJJ, Neef K, Strunk D, Zweigerdt R, de Jager SCA, Sluijter JPG. Journal of Cardiovascular Translational Research 2025. DOI: https://link.springer.com/article/10.1007/s12265-025-10596-0 READ THE FULL ARTICLE
T-cell repertoire correlates with cytokine imbalance in multiple sclerosis patients.
Weidner L, Poupardin R, Zrzavy T, Laner-Plamberger S, Gratz G, Eichhorn T, Weber V, Rommer PS, Jungbauer C, Strunk D. Frontiers in Immunology DOI: https://doi.org/10.3389/fimmu.2025.1604452 READ THE FULL ARTICLE
Selective EV Protein Sorting and Pathway Perturbation in AML Upon Synergistic FLT3 and Hedgehog Pathway Inhibition.
Blöchl C, Blümel G, Wolf M, Regl C, Binder H-M, Tesanovic S, Lankes D, Maeding N, Krenn PW, Strunk D, Aberger F, Huber CG. Journal of Extracellular Vesicles DOI: https://doi.org/10.1002/jev2.70163 READ THE FULL ARTICLE
Prime editing as a promising therapeutic strategy for junctional epidermolysis bullosa.
Ierl M, Bischof J, Liemberger B, Kocher T, Hainzl S, Gruner S, Trattner L, Reichl V, Klausegger A, Aussel C, Ammann S, Raab R, Andrieux G, Wolf M, Hochmann S, Ebner P, Wally V, Zauner R, Guttmann‑Gruber C, Gratz IK, Hofbauer JP, Cathomen T, Strunk D, Bauer JW, Koller. Molecular Therapy 2025. DOI: https://doi.org/10.1016/j.ymthe.2025.10.054 READ THE FULL ARTICLE
